Skip to main content
. 2009 Feb 15;20(4):1150–1166. doi: 10.1091/mbc.E08-06-0619

Figure 9.

Figure 9.

POC1 overexpression in human cells leads to elongated centriole-like structures, which is abolished when POC1 is knocked down by POC1 siRNA. (A) POC1B–GFP-expressing U2OS cells grown and treated with 3.2 μg/ml aphidicolin show a large percentage of cells with elongated centriole-like structures, which are POC1B-GFP positive and stain with Cetn2 (red). This overexpression phenotype is abolished in the presence of POC1 siRNA. (B) The percentage of cells with elongated centriole-like structures is dramatically reduced in the presence POC1 siRNA (left). The length of the elongated centriole-like structures was quantified and is also dramatically reduced in the presence of POC1 siRNA (right).