Table 3.
Summary of significant differences from time 1 to time 2 in developmental brain trajectories between 22q11.2DS and controls
Brain Area | % Difference
At Baseline1 |
% Change
22q11.2DS2 |
% Change
Controls2 |
F3 | P3 | Effect
Size4 |
---|---|---|---|---|---|---|
Amygdala | -9.1 | -1.71 | 0.23 | -6.5 | 0.01 | 0.16 |
Caudate Nucleus | -4.6 | 0.83 | -0.32 | 3.6 | 0.001 | 0.27 |
STG GM | 3.0 | -0.41 | -3.32 | 4.3 | <0.0001 | 0.38 |
Cranial WM | 20.9 | 1.61 | 0.30 | 2.3 | 0.03 | 0.13 |
Cerebellar WM | 48.0 | 19.1 | 0.97 | 3.5 | 0.002 | 0.25 |
STG GM: superior temporal gyrus grey matter; WM: white matter.
Percent difference between groups in structure volume at baseline.
Within group percent change per year from time 1 to time 2
Time x group interaction on repeated measures ANOVAs
Partial Eta2