Figure 3.

Effect on probe intensity of all possible single-base substitutions. Median intensity difference vs. MM substitution for all assayed regions in yeast (a) and human (b). Green curve is median intensity difference (MM-PM) for all instances of substitutions listed on the x-axis. Error bars represent ± σ for this curve. Blue curve: median intensity difference for high-intensity spots only (top 10% of spots by PM intensity). Red curve: median intensity difference for low-intensity spots (bottom 10% of spots by PM intensity).