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. 2007 Mar 14;13:366–373.

Table 1. Homozygous STOCK Crybb2Phil mice are subfertile.


Cryhh2+M x Crybb2+F
Crybh2PhilM x CrybbfPhilF
Mean Litter Size
(# of pups)
1 1.6±3.2
7.9±4.0
# of Litters
41
22
Mean Fecundity
(pups/30days)
9.2±4.8
4.6±3.6
# of matings
19
15
# of sterile matings
1 (5%)
3 (20%)
# of matings producing only one litter 3(16%) 7 (47%)

Crybb2+ M x Crybb2+ F versus Crybb2Phil M x Crybb2Phil F: Litter size p value=0.0002 Fecundity p value=0.0046.