Table 2. Both male and female homozygous STOCK Crybb2^Phil mice are subfertile.

	Crybh2+M x Crybh2+F	Cryhb2PhilM x *Cryhb2+F	Crybb2+M x Crybb2PhilF*
Mean Litter Size (# of pups)	12.7±2.5	9.5±3.4	7.9±2.0
Mean Fecundity (pups/30days)	12.8±4.0	5.4±4.2	4.4±4.0
N (# of matings)	8	8	5
# of sterile matings	0	2 (25%)	0
# of matings producing only one litter	0	2 (25%)	2 (40%)

*Female STOCK Crybb2^Phil homozygotes are not more significantly affected than male STOCK Crybb2^Phil homozygotes (Litter size p value=0.2231; Fecundity p value=0.6685) Litter size: Crybb2⁺ M x Crybb2⁺ F versus Crybb2^Phil M x Crybb2⁺ F: p value=0.003 Crybb2⁺ M x Crybb2⁺ F versus Crybb2⁺ M x Crybb2^Phil F: p value lt 0.001 Fecundity: Crybb2⁺ M x Crybb2⁺ F versus Crybb2⁺ F x Crybb2^Phil M: p value=0.003 Crybb2⁺ M x Crybb2⁺ F versus Crybb2⁺ M x Crybb2^Phil F: p value=0.004.