Table 3. Morphometric analysis of seminiferous tubule diameter of Swiss Webster and STOCK Crybb2^Phil homozygous mice.

	Crybb2+	Crybb2Phil	p-value
Newborn	52.4±6.5	51.6±7.3	13.83
1 week	66.5±7.1	59.9±6.2	2.3 x 10-9
2 week Mean	85.5±8.7	69.3±7.3	8.07 x 10-31
4 week Mean	161.9±18.5	177.7±23.8	1.36 x 10-5

At birth, the seminiferous tubule diameter (in μm) of wildtype and crybb2^phil mice was not statistically different. However, at one and two weeks postnatal when spermatogenesis is beginning, the tubule diameter of mutants is significantly smaller than wildtype. By four weeks of age, mutant seminiferous tubules become dilated relative to wildtype similar to the situation seen in adult animals.