Table 3. Genotypic frequencies of chemokine single nucleotide polymorphisms in patients and controls.
| Genotype |
Patients n=(141) |
Controls n=(282) |
|
| MCP-1 -2518 A/G |
AA |
58.2% |
53.4% |
| AG |
36.9% |
38.5% |
|
| GG |
5.0% |
8.1% |
|
| RANTES -403 G/A |
GG |
61.0% |
63.3% |
| GA |
34.8% |
31.8% |
|
| AA |
4.3% |
4.9% |
|
| RANTES -28 C/G |
CC |
94.3% |
94.3% |
| CG |
5.7% |
5.3% |
|
| GG |
0.0% |
0.4% |
|
| CCR2 V64I |
VV |
82.3% |
87.2% |
| VI |
16.3% |
12.5% |
|
| II |
1.4% |
0.4% |
|
| CCR5 -59029 G/A |
GG |
21.3% |
22.3% |
| GA |
44.7% |
48.6% |
|
| AA |
34.0% |
29.1% |
|
| CCR2 32 bp deletion | wt/wt |
77.3% |
76.6% |
| wt/del |
20.6% |
21.6% |
|
| del/del | 2.1% | 1.8% | |
The genotypic frequencies of the six polymorphisms were compared between patients and controls. The frequencies are shown in percentage and as seen in the table there are no significant differences between the genotypic frequencies of patients and controls.