Table 5.
| Table 5A: Relative IL-6 mRNA expression in various sites after ipo casein injection
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Leukocyt es | Air pouch cells | Liver | Spleen | Brain | Hypothalamus | Hippocampus | Pituitary | |
| ipo Vehicle | ND | ND | ND | ND | ND | ND | ND | ND |
| ipo Casein 4h | ND | *1.9±1.4 (×10−3) | ND | ND | ND | ND | ND | ND |
| ipo Casein 8h | ND | *2.0±0.3 (×10−3) | ND | ND | ND | ND | ND | ND |
| ipo LPS 6h | ND | *1.4±0.2 (×10−3) | ND | ND | ND | ND | ND | ND |
| Table 5B: IL-6 protein expression in various sites after ipo casein injection
| |||||
|---|---|---|---|---|---|
| Plasma (pg/ml) | Airpouch lavage (pg/ml) | Brain (pg/1mg protein) | Hypothalamus (pg/1mg protein) | Hippocampus (pg/1mg protein) | |
| ipo Vehicle | ND | 36±11 | 2.7±0.5 | ND | ND |
| ipo Casein 4h | *64±14 | *6625±554 | 3.5±1.0 | ND | ND |
| ipo Casein 8h | *87.5±16 | *6500±736 | 3.1±0.8 | ND | ND |
| ipo LPS 6h | *246±51 | *4253±565 | 3.6±0.7 | ND | ND |
IL-6 mRNA (A, IL-6/G3PDH) and protein (B) levels are shown. Values are means ± SEM (n=4).
Asterisk indicates significant difference (p<0.05) between vehicle-injected and inflammatory agents-injected animals. ND. Not Detectable