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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Dec 10;19(3):792–796. doi: 10.1016/j.bmcl.2008.12.031

Table 4.

Summary of permeability data for vidarabine and selected prodrugs

Compounds Caco-2 permeability cm/s × 106 Fold increase
Vidarabine (1) 0.083 —
D-val (7a) 0.601 7.2
L-ile (7k) 1.026 12.4
L-phe (7l) 0.668 8.05