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. 2009 Feb 23;4(2):e4563. doi: 10.1371/journal.pone.0004563

Table 1. Sources of patient's derived melanoma cells.

Melanoma Gender/age Stage/site BRAF status PTEN
WW165 F/62 Primary melanoma, 2.25 mm V600K (GTG->AAG) WT, Present*
YUMAC M/68 IV, Soft tissue metastasis, right thigh V600K (GTG->AAG) WT, Null (no protein)
YUGEN8 F/44 IV, Brain metastasis V600E (GTG->GAG) Null (no gene transcripts)
YUSAC2 M/57 IV, Soft tissue metastasis, left neck V600E (GTG->GAG) WT/LOH (Present)
YUSIT1 M/67 Metastatic melanoma V600K (GTG->AAG) WT (Present)
YULAC F/66 IV, Soft tissue metastasis, neck V600K (GTG->AAG) P38S/LOH (C1143T)
YURIF M/53 IV, Soft tissue metastasis, right thigh V600K (GTG->AAG) LOH Present
501 mel Not known Lymph node metastasis V600E (GTG->GAG) WT, Present
*

Present indicates normal levels of gene transcripts and protein expression compared to normal melanocytes. There was no induction of PTEN mRNA after Aza treatment.