Table 3.
Replication tests of rs1799990 and four novel candidate SNPs in patients with iCJD, patients with sCJD, and UK controls
| iCJD genotypes | UK control genotypes | Model | p (iCJD) | sCJD genotypes | Model | p (sCJD) | |
|---|---|---|---|---|---|---|---|
| rs1799990 | 4/13/11 | 294/324/81 | A | 2·7×10−4 | 307/98/101 | G | 2·3×10−21 |
| rs6107516 | 9/12/7 | 1960/1227/227 | R | 0·002 | 320/100/55 | G | 3·6×10−11 |
| rs6116492 | 28/0/0 | 2979/104/0 | A | 0·62 | 483/22/0 | A | 0·30 |
| rs1460163 | 0/7/21 | 31/657/2734 | A | 0·66 | 7/93/396 | A | 0·83 |
| rs6794719 | 1/8/19 | 346/1465/1596 | A | 0·03 | 61/207/207 | A | 0·08 |
Genetic models: A=allelic; G=genotypic; R=recessive.