Table 2. Lifetime risk of visual failure for Leber hereditary optic neuropathy carriers and recovery rates.
Pedigrees (n) | Median onset | Male: female ratio | Visual recovery (%) | Reference | |
m.3460G>A | 9 | 29 years | 2.3:1 | 22 | 22 |
8 | 20 years | 4.3:1 | 25 | 20 | |
m.11778G>A | 49 | 28 years | 4.5:1 | 4 | 21 |
66 | 24 years | 3.7:1 | 25 | 20 | |
10 | 29 years | 5.3:1 | 25 | 28 | |
m.14484T>C | 17 | 27 years | 2.1:1 | 37 | 23 |
23 | 19 years | 7.7:1 | 58 | 11 |