Figure 2.

Change in nasal neutrophil count and asthma symptoms during a cold compared with P2X₇ pore function. Baseline nasal lavage neutrophil counts and asthma symptoms were subtracted from the peak levels, respectively, to depict the corresponding changes in cold symptoms. Data are plotted against P2X₇ pore function assessed in whole blood samples by the fold change in agonist-induced dye uptake. The presence or absence of a loss of asthma control during a cold is denoted by open symbols and solid symbols, respectively. Spearman correlation coefficients for the entire data set are shown.