TABLE 1.
Acute Cold | Cold Resolution, Convalescent Baseline | |
---|---|---|
Peak cold symptom score | 17.8 ± 5.9 | 2.6 ± 3.6 |
Peak asthma symptom score | 7.7 ± 5.3 | 0.5 ± 1.4 |
FEV1, % predicted: mean ± SD | 89.2 ± 13.3 | 95.9 ± 12.1 |
Methacholine PC20, mg/ml: median (IQR) | 1.1 (0.4, 2.5) | 1.3 (0.6, 5.5) |
Virus detection | 22 participants, 18 with RV | Not determined |
Chlamydia pneumoniae/Mycoplasma pneumoniae serology | 0 participants with acute profile | 30 participants with prior exposure |
Definition of abbreviations: IQR = interquartile range; methacholine PC20 = provocative concentration of methacholine causing a 20% fall in FEV1; RV = rhinovirus.
Thirty-five participants were enrolled and 32 completed all visits. The median and interquartile range of the age distribution was 20 (18, 23) years. Seventeen of 35 participants were male. The lowest acute values of FEV1% predicted and methacholine PC20 are reported from participants with paired values at the convalescent baseline.