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. 2008 Jun;24(6):507–512. doi: 10.1016/s0828-282x(08)70627-5

TABLE 3.

Per cent absolute annual changes in prescription rates for antihypertensive drugs, comparison of three time periods

Drug Absolute annual changes in prescription rates, % (95% CI)
1999–2002 versus 1996–1998 2003–2006 versus 1996–1998 2003–2006 versus 1999–2002
Total antihypertensive 6.4 1.5 –4.7
  drugs (4.0 to 8.5) (–0.9 to 4.0) (–7.0 to –2.4)
Thiazide diuretics 8.9 3.9 –5.0
(4.3 to 13.5) (–1.0 to 8.8) (–9.6 to –0.4)
Angiotensin-converting 5.7 –1.3 –7.0
  enzyme inhibitors (1.9 to 9.6) (–5.4 to 2.8) (–10.9 to –3.2)
Angiotensin receptor –65.6 –66.8 –21.9
  blockers (–109.9 to –41.4) (–97.1 to –36.5) (–34.6 to –13.8)
Beta-blockers 3.6 0.8 –2.8
(1.6 to 5.6) (–1.3 to 2.9) (–4.8 to –0.8)
Calcium channel 6.2 4.7 –1.4
  blockers (3.2 to 9.2) (1.5 to 7.9) (–4.4 to 1.5)

Derived from the IMS CompuScript database (IMS Health Canada)