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Comparison of mucin content in bronchial biopsies from a healthy smoker and a patient with COPD. Representative sections from a healthy smoker (A–H) and a patient with COPD (I–P). Staining with H&E, PAS-alcian blue (PAS-AB), EuMUC5B (MUC5B), and MAN-5ACI (MUC5AC) at the surface epithelium (A–D and I–L), and in the submucosal glands (E–H and M–P) are shown. Sections from two other patients with COPD and one healthy smoker gave similar staining patterns.
