Figure 2.

FoxP3 and T-cell activation markers in peripheral blood mononuclear cells (PBMCs) of patients with tuberculosis-associated immune reconstitution inflammatory syndrome (TB–IRIS). PBMCs from 11 TB–IRIS and 8 non-IRIS patients were analyzed. Although the proportion of activated T cells (both CD4⁺ and CD8⁺) was high in both groups, there were no significant differences between clinical groups. For FoxP3 analysis cells were either unstimulated (unstim) or restimulated (stim) with PPD for 24 hours. Again, there were no significant differences between TB–IRIS and non-IRIS groups. Error bars show the SD.