TABLE 1.
DEFINITIONS OF CELL TYPES
| Stem cell | Cells with unlimited self renewal, dividing asymmetrically to produce an identical daughter cell and a more differentiated progenitor. |
| Bone marrow stem cell | Comprises hematopoietic and mesenchymal stem cells. |
| Hematopoietic stem cell | Stem cell able to form all cells of the blood lineage. |
| Mesenchymal stem cell | Stromal stem cell able to produce supporting cells including bone, fat, and cartilage. |
| Fibroblast | Main mature cell type involved in the production of the extracellular matrix and collagen of tissues. |
| Myofibroblast | Fibroblasts can be activated (e.g., by transforming growth factor β) to form these cells, which produce extracellular matrix but also have the ability to contract. Stain for α-smooth muscle actin. |
| Fibrocytes | Circulating peripheral cells of bone marrow origin. Often described as blood-derived fibroblasts. Express a characteristic pattern of markers including the leukocyte common antigen CD45, the hematopoietic marker CD34, and collagen 1. |