Figure 7.

Changes in RL (A) to inhaled MCh and BAL cellular composition (B). Anti–IFN-γ antibody or control rat IgG was administered to sensitized and seven OVA-challenged mice with RANTES treatment or PBS through the trachea. Forty-eight hours after the last OVA challenge, airway function measurements and BALF cell analysis were performed. The data are expressed as mean ± SEM. *P < 0.05 compared with RANTES and control rat IgG–treated mice with PBS and control rat IgG–treated mice. ^#P < 0.05 or ^##P < 0.01 between RANTES and anti–IFN-γ–treated mice versus RANTES and control rat IgG–treated mice, respectively. ⁺P < 0.05 or ⁺⁺P < 0.01 between PBS and anti–IFN-γ–treated mice versus PBS and control rat IgG–treated mice, respectively.