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. 2006 May 11;35(4):424–435. doi: 10.1165/rcmb.2005-0251OC

TABLE 5.

MODULATION OF GENES INVOLVED IN REDOX REGULATION

Category Description Hyp/Nor ratio P Value
Catalase and superoxide dismutase Catalase 1.27 0.084
Superoxide dismutase 1 1.05 0.683
Superoxide dismutase 2 1.38 0.687
Glutathione metabolism Glutathione peroxidase 1 1.51 0.35
Glutathione peroxidase 4 1.12 0.613
Glutathione peroxidase 2 0.92 0.798
Glutathione peroxidase 3 1.03 0.74
Glutathione-S-transferase A1 1.05 0.614
Glutathione-S-transferase A2 1.30 0.298
Glutathione-S-transferase A3 0.94 0.865
Glutathione-S-transferase A4 1.17 0.502
Glutathione-S-transferase M1 0.84 0.481
Glutathione-S-transferase M2 0.94 0.808
Glutathione-S-transferase M3 0.80 0.564
Glutathione-S-transferase M4 0.73 0.122
Glutathione-S-transferase M5 0.75 0.125
Glutathione-S-transferase pi 0.98 0.963
Glutathione-S-transferase subunit 13 1.09 0.636
Glutathione-S-transferase theta 1 0.98 0.952
Microsomal glutathione S-transferase 2 0.97 0.923
Glutathione-S-transferase omega 1 1.38 0.389
Glutathione synthetase 1 0.99
Glutamate cysteine ligase (catalytic subunit) 1.11 0.328
Glutamate cysteine ligase (modifier subunit) 1.17 0.217
Glutaredoxin 2 1.57 0.002
Glutaredoxin (thioltransferase) 1.38 0.118
Redox balance Ferredoxin 1 1.28 0.252
Ferredoxin reductase 1.11 0.656
Peroxiredoxin 1 1.05 0.587
Peroxiredoxin 2 1.00 1
Peroxiredoxin 3 1.18 0.079
Peroxiredoxin 4 1.34 0.396
Peroxiredoxin 6 1.18 0.181
Thioredoxin 1.24 0.387
Thioredoxin 2 1.11 0.697
Thioredoxin interacting protein 1.11 0.366
Thioredoxin reductase 1 1.06 0.691
Thioredoxin reductase 3 0.87 0.361
Thioredoxin like, 32kDa 1.15 0.274
Thioredoxin-like 2 0.98 0.839
Thioredoxin domain containing 1.16 0.478
Thioredoxin domain containing 4 1.04 0.681
Thioredoxin domain containing 5 1.04 0.864
Thioredoxin domain containing 7 1.31 0.024
Thioredoxin-related transmembrane protein 2 1.19 0.522
Alcohol dehydrogenase 1C 1.74 0.03
Alcohol dehydrogenase 5 1.33 0.02
Alcohol dehydrogenase 1A 0.96 0.792
Alcohol dehydrogenase 6 0.90 0.505
Alcohol dehydrogenase 7 1.22 0.442