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Effect of uPA on airway eosinophil adhesion to ICAM-1 (A) and VCAM-1 (B). Airway eosinophils were pretreated with buffer ± glycine, followed by incubation ± 125 nM uPA. For unstimulated cells: * P < 0.005 versus ICAM-1 adhesion (also versus blood eosinophil VCAM-1 adhesion: Figure 6); † P < 0.05 versus untreated and glycine-treated airway eosinophils; for FMLP-stimulated cells: ‡ P = 0.05 versus glycine-treated airway cells and untreated blood eosinophils (n = 8).
