Figure 2.
RSV attenuates ISO-induced cAMP formation (time course). Cultured HASM cells on each experimental day were infected with RSV (MOI 15; dark grey bars), UV-RSV (light grey bars), or mock infection (open bars) over three different time periods (2 h, 6 h, and 24 h), and then supernatant was harvested after ISO (10−6 M) stimulation for 10 min. Measurements were performed in duplicate in two separate experiments for each of four donors. Data are expressed as % maximal stimulation (Forskolin 10−4 M–induced cAMP formation). *P < 0.05 compared with baseline and compared with UV-RSV and with mock.