TABLE 5.
GENE ONTOLOGY CATEGORIES AND MEMBER GENES WITH SIGNIFICANTLY INCREASED EXPRESSION IN INDIVIDUALS WITH MILD CF LUNG DISEASE
| Name | Function | P Value |
|---|---|---|
| GO:0006629 | Lipid metabolism | 0.041 |
| ADIPOQ | Adiponectin | 0.026 |
| C21orf106 | DIP2-like protein | 0.024 |
| PLA2G5 | Phospholipase A2, group 5 | 0.046 |
| PPP2CA | Protein phosphatase 2 catalytic subunit | 0.049 |
| SCD4 | Stearyl-CoA desaturase | 0.031 |
| SFTPB | Surfactant, pulmonary protein B | 0.047 |
| GO:0006811 | Ion transport | 0.045 |
| SLC9A2 | Na/H exchanger | 0.045 |
| MINK | Potassium channel | 0.041 |
| FXYD2 | Na/H exchanger | 0.024 |
| COL7A1 | Collagen, phosphate transport regulation | 0.007 |
| ADIPOQ | Adiponectin | 0.026 |
| GO:0007186 | G-protein coupled receptor | 0.045 |
| PGF | Placental growth factor | 0.048 |
| HTR2A | Serotonin receptor 2A | 0.035 |
| GPR12 | G protein-coupled receptor 12 | 0.023 |
| C21orf106 | DIP2-like protein | 0.024 |
| GO:0030135 | Coated vesicle | 0.017 |
| SCD4 | Stearyl-CoA desaturase | 0.031 |
| SCAMP1 | Secretory carrier, post Golgi recycling | 0.045 |
| ADIPOQ | Adiponectin | 0.026 |
| GO:0005576 | Extracellular | 0.027 |
| STATH | Statherin | 0.020 |
| SFTPB | Surfactant, pulmonary protein B | 0.047 |
| PLA2G5 | Phospholipase A2, group 5 | 0.046 |
| PGF | Placental growth factor | 0.048 |
| LRRN1 | Leucine-rich repeat neuronal 1 | 0.032 |
| KLK13 | Kallikrein serine protease | 0.036 |
| COL7A1 | Collagen, phosphate transport regulation | 0.007 |
| ADIPOQ | Adiponectin | 0.026 |