TABLE 2.
GENES INDUCED 2-FOLD OR MORE IN IL-13–INDUCED RESOLUTION MODEL*
Common Gene Name | GenBank | DOX | DOX OFF |
---|---|---|---|
Arginase I | NM_007482 | + | − |
Arginase II | NM_009705 | + | − |
Ear11 | BC020070 | + | − |
MMP12 | BC019135 | + | − |
MMP13 | NM_008607 | + | − |
Adam8 | NM_007403 | + | − |
Cathepsin B | BG067383 | + | − |
Cathepsin S | NM_021281 | + | − |
Cathepsin Z | NM_022325 | + | − |
Dipeptidylpeptidase 7 | BB746075 | + | − |
Hexoaminidase A | U07631 | + | − |
Hexoaminidase B | NM_010422 | + | − |
Timp1 | BC008107 | + | − |
Serpina3g | BC002065 | + | − |
Serpinb2 | NM_011111 | + | − |
GLUT1 (Slc2a1) | BM207588 | + | − |
CAT2 (Slc7a2) | BF533509 | + | − |
Sglt1 (Slc5a1) | AF208031 | + | − |
cI-1 (Slc15a3) | NM_023044 | + | − |
Nramp-1 (Slc11a1) | NM_013612 | + | − |
C1q-β | AW227993 | + | − |
Complement component factor i | NM_007686 | + | − |
Inhibin-βa | NM_008380 | + | − |
Sprr-2a | NM_011468 | + | − |
Elastin | BB229377 | + | − |
Macrophage scavenger receptor 1 | BC003814 | + | − |
Lipocalin 2 | X14607 | + | − |
Complement component 3a receptor 1 | NM_009779 | + | − |
G protein–coupled receptor 35 | NM_022320 | + | − |
G protein–coupled receptor 43 | AV370830 | + | − |
G protein–coupled receptor 65 | NM_008152 | + | − |
Trem1 | BB784999 | + | − |
Trem2 | NM_031254 | + | − |
Toll-like receptor 8 | NM_133212 | + | − |
Toll-like receptor 7 | AY035889 | + | + |
MMP19 | AF153199 | + | + |
Ym2 (Chi3l3) | NM_009892 | + | + |
Brp39 (Chi3l1) | BC005611 | + | + |
Cathepsin K | NM_007802 | + | + |
Slc39a2 | BB049001 | + | + |
Slc26a4 | NM_011867 | + | + |
Mucolipin 3 | NM_134160 | + | + |
Clca1 | AF108501 | + | + |
Clca4 | AY008277 | − | + |
HSP105 | B1499717 | − | + |
Definition of abbreviations: DOX, mice fed doxycycline; DOX OFF, mice after 3 wk of doxycycline withdrawal.
If expression of the gene is induced at least ⩾ 2-fold compared with NO DOX controls, the gene is labeled with “+.” If transcript levels of the gene do not increase at least 2-fold, the gene is labeled with “−.” Genes induced ⩾ 2-fold in both groups are shown in bold type.