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. 2006 May 4;35(3):366–377. doi: 10.1165/rcmb.2005-0452OC

Figure 3.

Figure 3.

Treatment with pirfenidone suppresses mononuclear cell proliferation and in vitro cytokine production. OVA-stimulated PBLN mononuclear cell proliferation (A) and IL-4 (B), IL-5 (C), and IFN-γ (D) supernatant levels in mice after OVA sensitization and airway challenge were measured as described in Materials and Methods. The results for each group are expressed as the mean ± SD. n = 16 in each group. #Significant differences (P < 0.05) in treated PBLN mononuclear cell proliferation between the saline group and the pirfenidone-treated group. *Significant differences (P < 0.05) between the control group and the pirfenidone-treated group.