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. 2006 May 4;35(3):366–377. doi: 10.1165/rcmb.2005-0452OC

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Figure 5. — Effect of pirfenidone on inflammatory cell accumulation in peribronchial and perivascular tissue in nonsensitized/OVA-challenged mice (Non-sensitized/OVA), OVA-sensitized/OVA-challenged mice (OVA/OVA), and OVA-sensitized/OVA-challenged mice after repeated OVA exposure (4 wk-OVA/OVA). Evidence of inflammatory cell infiltration was investigated by histologic examination of hematoxylin-eosin–stained tissue as described in Materials and Methods (final magnification: ×400; inset: ×1,000). Bronchioles < 200 μm, 200–400 μm, and > 400 μm in diameter were selected. *Significant differences (P < 0.05) in the number of total cells, eosinophils, and lymphocytes in peribronchial and perivascular tissue between the saline-treated control group and the pirfenidone-treated group.