TABLE 2.

SERUM OVA-SPECIFIC ANTIBODY LEVELS

Groups	OVA-specific IgE Levels (EU/ml)	OVA-specific IgG1 Levels (EU/ml)
Nonsensitized/OVA/Control	31.4 ± 11.7	18.2 ± 8.1
Nonsensitized/OVA/PFD	26.2 ± 10.4	16.7 ± 9.5
OVA/OVA/Control	1046.8 ± 158.9*	418.0 ± 60.6*
OVA/OVA/PFD	582.7 ± 94.0#	267.2 ± 35.5

Definition of abbreviations: OVA, ovalbumin; PFD, pirfenidone.

^*Significant differences (P < 0.05) between OVA-sensitized/OVA-challenged control mice (receiving saline) (OVA/OVA/Control) and pirfenidone-treated mice (OVA/OVA/PFD). The results for each group are expressed as mean ± SD. n = 16 in each group.

^#Significant differences (P < 0.05) between nonsensitized/challenged mice (Nonsensitized/OVA/Control) and OVA-sensitized/OVA-challenged mice (OVA/OVA/Control).