TABLE 1.

siRNA SEQUENCES

Gene Name	siRNA Duplex No.	siRNA Sequence
Keap1	Duplex-1	Sense: 5′ GGACAAACCGCCUUAAUUCUU 3′
		Antisense: 3′ UUCCUGUUUGGCGGAAUUAAG 5′
	Duplex-2	Sense: 5′ CAGCAGAACUGUACCUGUUUU 3′
		Antisense: 3′ UUGUCGUCUUGACAUGGACAA 5′
	Duplex-3	Sense: 5′ GGGCGUGGCUGUCCUCAAUUU 3′
		Antisense: 3′ UUCCCGCACCGACAGGAGUUA 5′
	Duplex-4	Sense: 5′ CGAAUGAUCACAGCAAUGAUU 3′
		Anrisense: 3′ UUGCUUACUAGUGUCGUUACU 5′
Nrf2	Duplex-1	Sense: 5′ GAGAAAGAAUUGCCUGUAAUU 3′
		Antisense: 3′ UUCUCUUUCUUAACGGACAUU 5′
	Duplex-2	Sense: 5′ CCAAAGAGCAGUUCAAUGAUU 3′
		Antisense: 3′ UUGGUUUCUCGUCAAGUUACU 5′
	Duplex-3	Sense: 5′ GAAGCCAGAUGUUAAGAAAUU 3′
		Antisense: 3′ UUCUUCGGUCUACAAUUCUUU 5′
	Duplex-4	Sense: 5′ UAAAGUGGCUGCUCAGAAUUU 3′
		Antisense: 3′ UUAUUUCACCGACGAGUCUUA 5′
	siCONTROL Nontargeting	Sense: 5′ UAGCGACUAAACACAUCAAUU 3′
		Antisense: 3′ UUAUCGCUGAUUUGUGUAGUU 5′
GPX2		Sense: 5′ CCCUCUGGUUGGUGAUUCATT 3′
		Antisense: 3′ TTGGGAGACCAACCACUAAGU 5′

Definition of abbreviation: siRNA, small inhibitory RNA.