Figure 1.

The I353K mutation in the putative transmembrane region of RPS2. The putative transmembrane region of RPS2 protein (Middle) (7) is compared with the corresponding region of N (Top) (23). Identical and similar residues between the two proteins are indicated by vertical lines and colons, respectively, between the two sequences. The putative transmembrane region of RPS2, predicted by alom (22), is underlined. The corresponding region of the I353K mutant is shown at bottom. The mutated amino acid residue in I353K and the corresponding residues in N and RPS2 are shown in boldface. The numbers indicate the amino acid residue numbers in each protein.