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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: J Invest Dermatol. 2008 Jan 17;128(7):1780–1787. doi: 10.1038/sj.jid.5701251

Figure 1. Effect of UVB and CPAF on CHS in wild-type vs PAF-R−/− mice.

Figure 1

Wild-type and PAF-R−/− mice were treated with either (a) intraperitoneal injection of 250 ng of the PAF-R agonist CPAF or vehicle control, or (b) local irradiation with 0 (sham) or 7,500 J m−2 UVB. Mice were then sensitized to DNFB and elicitation reactions performed on the dorsal ears as outlined in Materials and Methods. At 24 hours after elicitation reactions, 5 mm punch biopsies were obtained from the ears and weighed. The data listed are the mean±SEM difference in ear biopsy weights from n = 6 mice. *Statistically (P<0.05) significant changes.