Table 3.
Oral Opioid Requirements and Sleep Disturbances
Oral Opioid,* mg |
Difficulty Sleeping,† Subjects per Group |
At Least One Awakening,† Subjects per Group |
||||
---|---|---|---|---|---|---|
Postoperative Day/Night | Ropivacaine Group | Placebo Group | Ropivacaine Group | Placebo Group | Ropivacaine Group | Placebo Group |
0 | 0 (0–10) | 0 (0–5) | 5 | 1 | 4 | 4 |
1 | 25 (10–50) | 40 (25–60) | 0 | 6 | 1 | 8 |
2 | 20 (5–30) | 25 (20–45) | 0 | 2 | 0 | 2 |
3 | 0 (0–10) | 10 (0–20) | 0 | 5 | 2 | 4 |
4 | 5 (0–12.5) | 15 (5–20) | 6 | 8 | 6 | 10 |
5 | 25 (10–40) | 20 (10–35) | 4 | 7 | 7 | 8 |
6 | 20 (5–40) | 20 (10–40) | ‡ | ‡ | ‡ | ‡ |
Because each comparison dilutes all other P values, we restricted our analysis to 11 comparisons among secondary endpoints. For this reason, no statistical comparisons were applied to the data of this table.
Values are reported as median (25th–75th percentiles) for nonparametric data. Includes only immediate-release oxycodone provided for breakthrough pain for the previous 24 h as of 18:00 each day, with the exception of postoperative day 0, which includes only the postanesthesia care unit (recovery room). Excludes sustained-release oxycodone (10 mg) provided to all patients twice daily.
As a result of surgical pain.
Data not collected.