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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Pharmacol Biochem Behav. 2009 Jan 6;92(2):304–313. doi: 10.1016/j.pbb.2008.12.019

Fig. 4.

Fig. 4

Abridged Ingenuity® Pathways Analysis of effects of ethanol in the nucleus accumbens shell of NP rats showing up-regulation of G-protein signaling pathways. Red indicates up-regulation, green indicates down-regulation, and clear symbol indicates proteins that were not identified as differentially expressed, but were linked to multiple proteins that had changed significantly. Solid lines indicate direct interactions and dashed lines indicate indirect interactions. Abbreviations: CD81 – Cd 81 protein; GNA12 – guanine nucleotide binding protein alpha 12; GNA13 – guanine nucleotide binding protein alpha 13; GNAQ - guanine nucleotide binding protein alpha q polypeptide; GNAI1 - guanine nucleotide binding protein (Gi) alpha-1 subunit; GNAI2 - guanine nucleotide binding protein (Gi) alpha-2 subunit; ROCK – Roh-associated coiled-coil containing protein kinase; THY1 – thymus cell antigen 1 theta or Thy-1 membrane glycoprotein precursor. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)