Table 4.
Significant GO categories containing 5 or more proteins that were different in the nucleus accumbens shell between the ethanol and control groups of NP rats
Function/Process | Up-regulated | Down-regulated |
---|---|---|
GTP-binding | Hexokinase-1; alpha-tubulin; Ras-related protein Rab-3B; guanine nucleotide binding protein alpha q polypeptide; Ac2-048 (Rab1); Atlastin-like protein; Galpha 13 | none |
ATP-binding | Hexokinase-1; sodium-potassium transporting ATPase alpha 2 chain precursor; sodium-potassium transporting ATPase alpha 1 chain precursor; Vacuolar ATPase subunit H; Ac2-048 (Rab1); NADH dehydrogenase 1 alpha subcomplex 10 | none |
DNA-binding | Unnamed protein product; Histone H2a; Histone H1.2; Histone H2A.Z; Histone H2A type 1; Histone H3.3 | Chain calmodulin; Zinc finger protein of the cerebellum 5 |
Protein binding | Dynein heavy chain; Unnamed protein product; Thy-1 membrane glycoprotein precursor; Prohibitin-2; Hexokinase-1; Syntaxin-binding protein-1; Sodium-potassium transporting ATPase alpha 2 chain precursor; Citrate synthase; Synaptic vesicle glycoprotein 2A; CD81 antigen; GTP-binding protein Rab-3D; Dual specificity mitogen-activated protein kinase kinase 1; Ras-related protein Rab-3A | Chain calmodulin; Prohibitin; Calmodulin; Nucleoside di-phosphate kinase B |