Table 5.
Priority 1 (>99.9% confidence level) proteins that were significantly (p-values < 0.015; q-values < 0.2) different and changed by 15% or greater in the nucleus accumbens shell between the ethanol-injected (E) and control (C) Wistar (W) rats
| Protein ID | Gene symbol | Annotation | WE/WC |
|---|---|---|---|
| IPI00782125.1 | 13_kDa_protein | -1.28 | |
| IPI00362291.1 | 16_kDa_protein | -1.15b | |
| IPI00189519.1 | 19_kDa_protein | -1.17c | |
| IPI00568873.2 | 20_kDa_protein | -1.41 | |
| IPI00562632.1 | 33_kDa_protein | 1.22a | |
| IPI00366110.3 | 47_kDa_protein | -1.16 | |
| IPI00777829.1 | 54_kDa_protein | 1.28 | |
| 15986733 | Rab4b | AF408432_1_GTP-binding_protein_RAB4_[Mus_musculus] | -1.19a |
| IPI00215523.1 | Bcat1 | Branched-chain-amino-acid_aminotransferase,_cytosolic | -1.17 |
| IPI00231118.4 | Calb1 | Calbindin | -1.15a |
| IPI00566635.2 | Discs_large_homolog_4 | 1.20 | |
| IPI00231733.6 | Gnai1 | Guanine_nucleotide-binding_protein_G(i),_alpha-1_subunit | 1.19a,b |
| IPI00231650.6 | Hist1h1c | Histone_H1.2 | 1.15b |
| IPI00417225.1 | Synpo | Isoform_1_of_Synaptopodin | 1.18a |
| IPI00202549.1 | Pklr | Isoform_R-type_of_Pyruvate_kinase_isozymes_R/L | 1.21 |
| 66857 | KIRTPR_pyruvate_kinase_(EC_2.7.1.40),_erythrocyte_splice_form_R_-_rat | 1.27 | |
| 26006161 | mKIAA0417_protein_[Mus_musculus] | 1.15 | |
| IPI00191790.1 | Efcbp2 | Neuronal_calcium_binding_protein_NECAB2 | -1.15 |
| IPI00231641.4 | Pgm1 | Phosphoglucomutase-1 | 1.30a,b |
| IPI00199203.1 | Gapdh | PREDICTED:_similar_to_glyceraldehyde-3-phosphate_dehydrogenase | 1.24 |
| IPI00358537.2 | Hspa12a | PREDICTED:_similar_to_heat_shock_protein_12A | 1.15 |
| IPI00464820.4 | Ngef | PREDICTED:_similar_to_neuronal_guanine_nucleotide_exchange_factor | 1.53a |
| IPI00763565.1 | PREDICTED:_similar_to_polyubiquitin | -1.41 | |
| IPI00190240.1 | Rps27a | Ribosomal_protein_S27a | -1.38 |
| IPI00471526.3 | LOC298795 | Similar_to_14-3-3_protein_sigma | -1.23 |
| IPI00394488.2 | LOC498174 | Similar_to_NipSnap2_protein | 1.30a |
| 54038641 | Tagln2 | Transgelin_2_[Rattus_norvegicus] | -1.15 |
| IPI00215349.3 | Wdr1 | WD_repeat_protein_1 | 1.22a,b |
WE/WC = fold change ethanol over control value; minus sign indicates that WC value was greater than WE value; n = 10 for WC, and n = 9 for WE.
a
Similar ratio change found for P rats;
b
similar ratio change observed for NP rats;
c
opposite ratio change found for NP rats.