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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Kidney Int. 2008 Oct 8;75(5):465–474. doi: 10.1038/ki.2008.496

Figure 6. Ferumoxides but not ferumoxtran-10 nor ferumoxytol (even in the presence of protamine sulfate) label circulating rat mononuclear cells after intravenous infusion.

Figure 6

Female Long Evans rats received IV ferumoxides, ferumoxtran-10, or ferumoxytol (20 mg/kg) with or without preincubation with protamine sulfate (Pro) (2 mg/kg). (a) Mononuclear cells were isolated from peripheral circulation 2 h after injection and stained with DAB-enhanced Perl's blue. Iron-labeled cells with brown stain are indicated by arrowheads. (b) Percentage of iron-positive-stained cells in total mononuclear cell population. (c) Time course of ferumoxide-Pro in vivo iron-labeled rat mononuclear cells. Data are represented as mean ± s.e.m.7 (Used with permission from Am J Physiol Cell Physiol 2007; 293: C1698–C1708).