Table 2.
Overall N=1482 |
Low Risk2 N=537 |
Intermediate Risk2 N=459 |
High Risk2 N=209 |
P value | |
---|---|---|---|---|---|
Concern about the implications of my CLL for my family/loved ones | 5.1 | 4.0 | 5.0 | 7.0 | <0.001 |
Uncertainty about whether my CLL will progress | 4.3 | 3.9 | 4.4 | 5.4 | <0.001 |
Concern about the side effects of treatment for my CLL | 4.1 | 3.3 | 4.3 | 5.6 | <0.001 |
Concern my children or relatives may also develop CLL | 3.6 | 3.5 | 3.8 | 3.9 | 0.396 |
Generalized worry about having CLL | 3.6 | 3.1 | 3.6 | 4.6 | <0.001 |
Living with symptoms related to CLL (fatigue, weight loss, night sweats, infections) | 3.5 | 2.0 | 3.0 | 6.0 | <0.001 |
Patients were asked to rate how much each item negatively affected their quality of life on a 0–10 Likert scale where 0 = “no effect on my quality of life” and 10 = “major negative effect on my QOL”. Items are shown in hierarchical order of importance to CLL patients based on mean scores.
Risk refers to patients stage using the modified Rai risk categorization28