Table 2.

 Logistic regression models illustrating odds of cognitive impairment (95% confidence intervals) in 4809 non-smokers by salivary cotinine levels

Variable	Basic adjusted model*	Fully adjusted model†	Fully adjusted model plus medical history‡
Salivary cotinine fourths (ng/ml):
Lowest (0.0-0.1)	Reference	Reference	Reference
Second (0.2-0.3)	1.13 (0.83 to 1.54)	1.08 (0.78 to 1.48)	1.08 (0.79 to 1.48)
Third (0.4-0.7)	1.26 (0.92 to 1.72)	1.13 (0.81 to 1.56)	1.12 (0.81 to 1.56)
Highest (0.8-13.5)	1.68 (1.27 to 2.22)	1.44 (1.07 to 1.94)	1.44 (1.07 to 1.93)
P for trend	<0.001	0.02	0.02

Population weights used to adjust for sampling design.

*Adjusted for age, sex, education, and testing interval.

†Adjusted for age, sex, education, testing interval, ethnicity, manual occupation, net wealth, smoking history, obesity, alcohol consumption, physical inactivity, and depressive symptoms.

‡Adjusted for age, sex, education, testing interval, ethnicity, manual occupation, net wealth, smoking history, obesity, alcohol consumption, physical inactivity, depressive symptoms, history of medical conditions (diabetes, cardiovascular disease, stroke, untreated hypertension, and hypertension treated with antihypertensive drugs).