Table 3.
Logistic regression models illustrating odds of cognitive impairment (95% confidence intervals) in former and never smokers by salivary cotinine levels
| Variable | Never smokers (n=2014) | Former smokers (n=2795) | |||
|---|---|---|---|---|---|
| Basic adjusted model* | Fully adjusted model† | Basic adjusted model* | Fully adjusted model† | ||
| Salivary cotinine fourths (ng/ml): | |||||
| Lowest (0.0-0.1) | Reference | Reference | Reference | Reference | |
| Second (0.2-0.3) | 1.44 (0.90 to 2.31) | 1.42 (0.88 to 2.31) | 0.95 (0.63 to 1.45) | 0.88 (0.57 to 1.34) | |
| Third (0.4-0.7) | 1.26 (0.77 to 2.08) | 1.16 (0.68 to 1.97) | 1.26 (0.85 to 1.86) | 1.11 (0.74 to 1.67) | |
| Highest (0.8-13.5) | 1.75 (1.10 to 2.78) | 1.70 (1.03 to 2.80) | 1.62 (1.14 to 2.30) | 1.32 (0.92 to 1.91) | |
| P for trend | 0.03 | 0.08 | 0.005 | 0.1 | |
Population weights used to adjust for sampling design.
*Adjusted for age, sex, education, and testing interval.
†Adjusted for age, sex, education, testing interval, ethnicity, manual occupation, net wealth, smoking history, obesity, alcohol consumption, physical inactivity, and depressive symptoms.