TABLE 1.
Analysis of lipid droplet size from cells expressing DGAT1, DGAT2, and MGAT2 that were incubated with 0.5 mm oleate for 12 h
|
Lipid droplet
|
Diameter (μm)
|
||||
|---|---|---|---|---|---|
| Control | DGAT2 | DGAT1 | MGAT2 | ||
| With oleate | 1.99 ± 0.33 | 4.11 ± 1.02a | 2.06 ± 0.20 | 1.89 ± 0.39 | |
|
Number/cell
|
|||||
| Without oleate | 131.2 ± 46.5 | 214.7 ± 60.7 | 147.0 ± 47.0 | 135.3 ± 9.5 | |
| With oleate | 88.0 ± 8.3 | 37.8 ± 11.7b | 269.7 ± 54.9c,d | 148.0 ± 43.7 | |
p < 0.001 versus control-transfected cells.
p < 0.001 versus DGAT2-expressing cells.
p < 0.001 versus oleate-loaded, control-transfected cells.
p < 0.05 versus DGAT1-expressing cells.