TABLE 4.
Tilt angles of NAGK or NAGK-like dimers relative to the plane of the hexameric ring
| Protein Data Bank code | Organisms | Substrates | Effectors | Angle | References |
|---|---|---|---|---|---|
| 2R8V | N. gonorrhoeae | AcCoA | None | 39.5 | Ref. 6 |
| 2R98 | N. gonorrhoeae | CoA + NAG | None | 39.6 | Ref. 6 |
| 3D2M | N. gonorrhoeae | CoA + Glu | None | 39.7 | Present work |
| 3D2P | N. gonorrhoeae | CoA | Arg | 36.0 | Present work |
| 2BTY | T. maritima | None | Arg | 33.5 | Ref. 5 |
| 2BUF | P. aeruginosa | None | None | 41.5 | Ref. 5 |
| 2RD5 | A. thaliana | ADP+NAG | PII+Arg+ADP | 38.5 | Ref. 30 |
| 2V5H | Synechococcus elongatus | NAG | PII | 38.3 | Ref. 31 |
| 2AP9 | M. tuberculosis | None | Nonea | 35.2 | K. R. Rajashankar, R. Kniewel, K. Lee, and C. D. Lima, to be published |
a
Calculated tilt angle is close to that predicted for T-state conformation. Whether L-arginine might be bound in this structure needs to be further investigated.