TABLE 1.
Pathogenicities, measured by LC50 and LC90, of four virus isolates on C. pomonella laboratory colonies susceptible (Sv) and resistant (RGV) to CpGV-Ma
| Strain (yr) | Virus | No. of insects tested | No. of OBs/μl (95% CI)
|
Slope ± SE | χ2 | Resistance factor (fold)
|
||
|---|---|---|---|---|---|---|---|---|
| LC50 | LC90 | LC50 | LC90 | |||||
| Sv (2007) | CpGV-M07 | 771 | 24.00 (14.10-35.86) | 275.45 (176.83-512.48) | 1.21 ± 0.12 | 1.11 | 1 | 1 |
| I12 | 486 | 26.10 (13.8-41.8) | 261.82 (149.04-652.39) | 1.28 ± 0.19 | 4.70 | 1 | 1 | |
| NPP-R1 | 689 | 25.80 (14.48-39.93) | 328.55 (196.93-702.51) | 1.16 ± 0.13 | 1.28 | 1 | 1 | |
| Sv (2008) | CpGV-M08 | 593 | 29.22 (13.87-49.27) | 377.37 (231.96-725.56) | 1.15 ± 0.14 | 3.07 | 1 | 1 |
| 2016-r4 | 999 | 39.65 (6.40-133.91) | 805.85 (260.20-1.36 × 103) | 0.98 ± 0.11 | 13.6 | 1 | 2 | |
| RGV.4 (2007) | CpGV-M07 | 416 | 1.38 × 106 (3.17 × 105-4.91 × 106) | NAb | 0.62 ± 0.12 | 1.61 | 60,000 | NA |
| I12 | 656 | 5.01 × 103 (1.85 × 103-1.03 × 104) | 2.74 × 105 (1.27 × 105-8.35 × 105) | 0.63 ± 0.08 | 4.42 | 200 | 1,000 | |
| NPP-R1 | 578 | 166.31 (91.21-278.27) | 1.28 × 104 (5.95 × 103-3.80 × 104) | 0.70 ± 0.08 | 4.81 | 7 | 46 | |
| RGV.8 (2008) | CpGV-M08 | 698 | 2.37 × 106 (8.53 × 105-7.61 × 106) | NA | 0.50 ± 0.10 | 4.62 | 80,000 | NA |
| 2016-r4 | 1,201 | 102.31 (63.20-146.91) | 1.57 × 103 (1.01 × 103-2.97 × 103) | 1.10 ± 0.10 | 6.21 | 3.5 | 4 | |
a
The pathogenicity of CpGV-M for Sv larvae is used as a reference level. Bioassays were carried out by diet surface contamination with neonate larvae. Mortality was scored 7 days after infection.
b
NA, >50% mortality could not be achieved on RGV larvae inoculated with CpGV-M isolates.