TABLE 2.

Overrepresented gene categories for K-means clusters^a

Group	Overrepresented gene categories
K1	Protein biosynthesis, small-GTPase-mediated signal transduction, calcium ion transport, protein folding
K2	rRNA processing, transcription, ribosome biogenesis, purine nucleotide biosynthesis, cell adhesion, amino acid metabolism
K3	Protein biosynthesis, glycolysis
K4	Translation initiation factor activity, protein biosynthesis, carbohydrate transport, oligopeptide transport, cell cycle
K5	Tricarboxylic acid cycle, glycolysis, fatty acid biosynthesis, anion transport, GTP biosynthesis, UTP biosynthesis, protein nucleus import
K6	Chitin synthase activity, proton transport
K7	Signal transduction, actin-binding activity
K8	Ion channel activity
K9	Amino acid transport, intracellular protein transport, protein serine/threonine kinase activity, calcium ion-binding activity, signal transducer activity
K10	Chromosome organization and biogenesis

^aA functional category was considered overrepresented if its statistical association with its presence in the cluster was significant (P < 0.05) (see Fig. 2).