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Incidence of plague in mice infected with the Y. pestis 195/P Δcaf1M1A1::aph strain after flea bite challenge
| Mouse no. | No. of challenges (median, 3) | Total no. of flea bites (cumulative) (median, 49) | No. of blocked flea bites (cumulative) (median, 7.5) | Time to onset of disease (days) (median, 3) | Outcomea |
|---|---|---|---|---|---|
| 1 | 1 | 17 | 7 | 3 | B |
| 2 | 2 | 30 | 8 | 3 | B |
| 3 | 2 | 37 | 8 | 4 | B |
| 4 | 2 | 42 | 11 | 3 | S |
| 5 | 3 | 56 | 7 | − | |
| 6 | 3 | 63 | 8 | − | |
| 7 | 4 | 71 | 4 | − | |
| 8 | 4 | 59 | 5 | − | |
| 9 | 4 | 41 | 6 | − | |
| 10 | 4 | 79 | 8 | − |
B, bubonic plague; S, septicemic plague; −, no disease.
