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. 2009 Jan 12;77(3):1165–1174. doi: 10.1128/IAI.01129-08

FIG. 4.

FIG. 4.

Association between age and IgG subclass reactivity to different merozoite antigens. The proportions of individuals who were positive for IgG1 and IgG3 for each age group are shown (0 to 3 years [n = 50], 4 to 6 years [n = 48], 7 to 9 years [n = 50], and >10 years [n = 59]). Associations between IgG subclass responses and age were significant for all antigens (for MSP1-19, P < 0.001 and P = 0.018 for IgG1 and IgG3, respectively; for AMA-1, P < 0.0001 for IgG1 and IgG3; for MSP2 3D7, P = 0.002 and P < 0.0001 for IgG1 and IgG3, respectively; and for MSP2 FC27, P < 0.0001 for IgG1 and IgG3). The 3D7 allele of MSP1-19 and AMA-1 was used.