TABLE 2.
Viral load and viral genome physical status of HPV18 infection according to the degree of cervical lesion
| Cervical lesion type (n) | Viral load measurement (mean [interquartile range])
|
Form of the viral genome (no. of samples [%])
|
Type of HPV infection (no. of samples [%])
|
|||||
|---|---|---|---|---|---|---|---|---|
| Crude total viral load (copies/μl) | Beta-actin level (copies/μl) | Normalized viral load (copies/cell equivalent) | Pure episomal | Pure integrated | Concomitant | Single | Coinfectiona | |
| Normal/LGSIL/CIN 1 (12) | 255.1 (118.3-6,949.7) | 36.6 (1.9-392.1) | 6.8 (2.0-245.0) | 7 (58.3) | 3 (25.0) | 2 (16.7) | 4 (33.3) | 8 (66.7) |
| CIN 2/CIN 3 (24) | 1,069.8 (225.2-8,784.5) | 251.5 (7.1-1,237.2) | 21.9 (2.3-140.3) | 16 (66.7) | 6 (25.0) | 2 (8.3) | 14 (58.3) | 10 (41.7) |
| ICC (42) | 58,985.0 (3,215.0-477,860.7) | 5,578.5 (1,452.7-20,193.6) | 11.7 (3.5-53.4) | 24 (57.1) | 11 (26.2) | 7 (16.7) | 28 (66.7) | 14 (33.3) |
a
Coinfection with other HPV type(s).