TABLE 2.
Results of C. jejuni gene association testing for comparison of CGH CE and HE groupsa
| Gene | No. absent from CGH CE clusters (n = 27) | No. absent from CGH HE clusters (n = 24) | CGH CE vs HE P value
|
Gene product | |
|---|---|---|---|---|---|
| Unadjusted | WY | ||||
| Cj0202 | 27 | 14 | 0.00015 | 0.00210 | Hypothetical protein |
| Cj0300 | 19 | 24 | 0.00464 | 0.05000 | Putative molybdenum transport ATP-binding protein |
| Cj0302 | 16 | 24 | 0.00033 | 0.00400 | Putative molybdenum-pterin binding protein |
| Cj0303 | 11 | 24 | <0.00001 | <0.00001 | Putative molybdate-binding lipoprotein |
| Cj0304 | 15 | 24 | 0.00013 | 0.00135 | Putative biotin synthesis protein |
| Cj0399 | 17 | 24 | 0.00081 | 0.01145 | Colicin V production protein homolog |
| Cj0485 | 13 | 21 | 0.00352 | 0.03890 | Putative oxidoreductase |
| Cj0617 | 27 | 6 | <0.00001 | <0.00001 | Hypothetical protein |
| Cj0628 | 0 | 8 | 0.00116 | 0.01525 | Putative lipoprotein |
| Cj1051 | 2 | 12 | 0.00118 | 0.01555 | Restriction modification enzyme |
| Cj1136 | 3 | 16 | 0.00005 | 0.00055 | Putative glycosyltransferase |
| Cj1137 | 4 | 17 | 0.00006 | 0.00085 | Putative glycosyltransferase |
| Cj1138 | 5 | 17 | 0.00023 | 0.00325 | Putative glycosyltransferase |
| Cj1139 | 10 | 22 | 0.00010 | 0.00115 | β-1,3-Galactosyltransferase |
| Cj1140 | 9 | 19 | 0.00172 | 0.01970 | α-2,3-Sialyltransferase |
| Cj1141 | 3 | 17 | 0.00001 | 0.00005 | Sialic acid synthase (N-acetylneuraminic acid synthetase) |
| Cj1142 | 6 | 18 | 0.00023 | 0.00360 | Putative UDP-N-acetylglucosamine 2-epimerase |
| Cj1143 | 2 | 16 | 0.00002 | 0.00010 | Two-domain bifunctional protein (β-1,4-N-acetylgalactosaminyltransferase/CMP-Neu5Ac synthase) |
| Cj1144 | 6 | 16 | 0.00194 | 0.02315 | Hypothetical protein |
| Cj1145 | 5 | 16 | 0.00066 | 0.00885 | Coding sequence merged with Cj1144 |
| Cj1146 | 12 | 22 | 0.00038 | 0.00455 | Putative glucosyltransferase |
| Cj1150 | 19 | 24 | 0.00464 | 0.05000 | d-β-d-Heptose 7-phosphate kinase/d-β-d-heptose 1-phosphate adenylyltransferase |
| Cj1297 | 10 | 19 | 0.00424 | 0.04385 | Hypothetical protein |
| Cj1389 | 1 | 16 | <0.00001 | <0.00001 | Pseudogene (putative C4-dicarboxylate anaerobic carrier |
| Cj1421 | 6 | 18 | 0.00023 | 0.00360 | Putative sugar transferase |
| Cj1422 | 7 | 20 | 0.00006 | 0.00080 | Putative sugar transferase |
| Cj1428 | 10 | 20 | 0.00145 | 0.01710 | GDP-l-fucose synthetase |
| Cj1429 | 6 | 19 | 0.00007 | 0.00090 | Hypothetical protein |
| Cj1430 | 8 | 18 | 0.00191 | 0.02225 | Putative dTDP-4-dehydrorhamnose 3,5-epimerase |
| Cj1432 | 3 | 16 | 0.00005 | 0.00055 | Putative sugar transferase |
| Cj1433 | 2 | 17 | <0.00001 | <0.00001 | Hypothetical protein |
| Cj1434 | 5 | 19 | 0.00002 | 0.00025 | Putative sugar transferase |
| Cj1435 | 8 | 19 | 0.00105 | 0.01410 | Putative phosphatase |
| Cj1439 | 0 | 15 | <0.00001 | <0.00001 | UDP-galactopyranose mutase |
| Cj1440 | 6 | 16 | 0.00194 | 0.02315 | Putative sugar transferase |
| Cj1520 | 9 | 20 | 0.00054 | 0.00665 | Removed from coding sequences |
| Cj1729 | 1 | 13 | 0.00007 | 0.00150 | Flagellar hook subunit protein |
a
All genes are statistically significant (P ≤ 0.05) based on the unadjusted Fisher's exact test P values and the WY corrected P values; 1,399 genes were tested. The gene product information is from reference 14.