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. 2008 Dec 17;83(5):2349–2356. doi: 10.1128/JVI.00821-08

TABLE 1.

Estimates of a replicative enhancement factor

Study R0
Difference Ratio (range)a
Chowers et al. (6) 2.2 1:36, 2:10
Miller et al. (34) 0.79 1:12, 1:37
Spina et al. (39) 0.74 1:31, 1:40
a

Assumes R0 of the Nef-defective strain in the interval [2:0, 6:0].