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. 2008 Dec 17;83(5):2349–2356. doi: 10.1128/JVI.00821-08

TABLE A2.

Parameters in the in vivo CD8 modelb

Parameter Symbol Value (for rates, per day)
Resting activation α (2-5) × 10−10
NR “immigration” β See text
NR death rate δNR 0.00017
MR death rate δMR 0.00017 or 0.333
CTL death rate δCTL 0.333
Reversion fraction Revert 0.05
No. of doublings ηd 8
Naïve cell cycles/day 2.0
Memory cell cycles/day 4.0
Naïve cell cycles before ES 4
Memory cell cycles before ES 1
Memory speed-up factor 7.0
a

Defined quantities: NR, naïve resting cells; MR, memory resting cells; ηd, number of programmed-proliferation divisions; ES, effector status.