TABLE A2.
Parameter | Symbol | Value (for rates, per day) |
---|---|---|
Resting activation | α | (2-5) × 10−10 |
NR “immigration” | β | See text |
NR death rate | δNR | 0.00017 |
MR death rate | δMR | 0.00017 or 0.333 |
CTL death rate | δCTL | 0.333 |
Reversion fraction | Revert | 0.05 |
No. of doublings | ηd | 8 |
Naïve cell cycles/day | 2.0 | |
Memory cell cycles/day | 4.0 | |
Naïve cell cycles before ES | 4 | |
Memory cell cycles before ES | 1 | |
Memory speed-up factor | 7.0 |
Defined quantities: NR, naïve resting cells; MR, memory resting cells; ηd, number of programmed-proliferation divisions; ES, effector status.