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. 2008 Dec 10;83(5):2226–2236. doi: 10.1128/JVI.01655-08

FIG. 5.

FIG. 5.

CCR5−/− mice are permissive for influenza A/WSN/33 virus infection. (A) Groups of female mice (n = 6), age 6 to 8 weeks, were infected with 0.1 HAU influenza A/WSN/33 virus and body weight measured daily. Body weight loss was expressed as the mean percent weight loss of animals at the indicated time points compared to that of controls ± standard errors. ▪, CCR5+/+; ░⃞, CCR5−/−. (B) Lungs of mock- and influenza A/WSN/33 virus-infected CCR5+/+ and CCR5−/− mice harvested on days 3 and 6 p.i. were fixed in 2% paraformaldehyde and embedded in paraffin, and 6-μm-thick histological sections were prepared and stained with hematoxylin and eosin.