FIG. 3.
The gB498-nonspecific CD8 T-cell population displays a more diverse Vβ TCR usage. TG were harvested at 8 dpi, pooled, and stained with gB498 tetramers, for CD8, and for TCR Vβ utilization. (A) Representative histograms illustrate utilization of three prominent Vβ (Vβ 5.1, 5.2, Vβ 8.1, 8.2, and Vβ 10b) TCR segments by gB498 tetramer-positive (gB498-specific) and gB498 tetramer-negative (gB498-nonspecific) CD8 T cells. Numbers within histograms correspond to the percentage of cells within the positive gate. (B and C) Data are presented graphically as the percent expression of indicated Vβ TCR among gB498-specific CD8 T cells (B) or gB498-nonspecific CD8 T cells (C).